Study: Septic shock drug shortage associated with higher mortality in 2011

AHA News Now

The U.S. norepinephrine shortage in 2011 was associated with increased mortality among hospital patients with septic shock, according to a study published online yesterday by the Journal of the American Medical Association. The Food and Drug Administration reported a severe nationwide shortage of norepinephrine in 2011 due to production interruptions at three drug manufacturers. The study found that septic shock patients at hospitals experiencing a norepinephrine shortage had a 3.7% higher rate of in-hospital mortality, based on a retrospective analysis of administrative and pharmacy billing data from the Premier Healthcare Database. The Food and Drug Administration Safety and Innovation Act of 2012 included a number of AHA-supported provisions to help alleviate critical drug shortages.

Topic: Advocacy and Public Policy
Tag: Drug Shortages

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